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SGC-CBP30 Table shows all AP courses taken by participants i
2020-08-17
Table 5 shows all AP courses taken by participants, in descending order with respect to percentage of higher-order keywords. Table 5 also includes t-tests of mean differences for average CPA exam scores of participants who have taken (vs. not taken) AP courses (AP_ENGAGE), and average CPA exam score
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POE specialises Rogers definition of engineering to systems
2020-08-17
POE specialises Rogers\' definition of engineering [37] to systems engineering as: As such, systems engineering becomes a problem solving exercise, the problem being, given a physical environment E, to find the system S that EZLink Sulfo-NHS-SS-Biotin Kit sale meets a real-world need N to the satis
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NPC L NPC Niemann Pick C
2020-08-17
NPC1L1 (NPC1 [Niemann-Pick C-like-1]-like intracellular cholesterol transporter) is the rate-limiting transmembrane transporter for cholesterol glasdegib sale from the intestinal lumen, and it mediates the absorption of both dietary and biliary cholesterol., , NPC1L1 is the target of the cholester
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br Materials and methods br Results br Discussion
2020-08-17
Materials and methods Results Discussion PKA and Epac are two principal effector proteins involved in cAMP signaling; they are expressed in a wide range of tissues and control diverse biological functions [10]. The existence of two cAMP effectors provides more precise regulation of cAMP sig
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The liposomes as a FDA approved drug delivery
2020-08-17
The liposomes, as a FDA-approved drug delivery carrier, have been widely utilized for drug delivery [32], [33], [34]. Liposomes are defined as self-assembled vesicles, which are composed of one or multiple concentric lipid bilayers and enclose an aqueous core. The advantages of utilizing liposomes a
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br Acknowledgements This research was supported by Slovenian
2020-08-17
Acknowledgements This research was supported by Slovenian Research Agency (ARRS). We thank prof. R. Marinšek Logar for helpful advice, Dr. T. Kranjc for help with data management, N. Vrhovnik and G. Lavrič for technical help with preliminary growth experiments and dr. J. Burkeljca for help with g
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Based on the similar activities of
2020-08-15
Based on the similar activities of Rad6p and Cdc34p (i.e., both are E2 ub-conjugating enzymes) on ubiquitinylation of p33 replication protein, we propose that Rad6p and the plant Ubc2p mono- and bi-ubiquitinate the viral replication proteins in order to facilitate the recruitment of the cellular ESC
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br Conflict of interest br Acknowledgments
2020-08-14
Conflict of interest Acknowledgments We thank Jianru Zuo (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) for providing fbr11-1 seeds. We are grateful to Carol MacKintosh and the DSTT at the University of Dundee (UK) for anti-RD21 antibodies. This
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The synthetic routes to the substrates
2020-08-14
The synthetic routes to the substrates based on the 2,3-dihydroxynaphthalene and 6,7-dibromo-2,3-dihydroxynaphthalene cores are depicted in Scheme 3. A Michael-type glycosylation of 2,3-dihydroxynaphthalene 16a gave the acetylated sugar 17a which was deprotected giving the required β-glucosidase sub
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Tropical theileriosis is caused by the apicomplexan
2020-08-14
Tropical theileriosis is caused by the apicomplexan parasite Theileria annulata which is transmitted by a tick vector from the genus Hyalomma in cattle (Echebli et al., 2014, Li et al., 2014). Theileria parasites invade the leukocytes by sporozoites secreted from the vector, schizonts mature into me
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br Authors contributions br Acknowledgements br Introduction
2020-08-14
Authors’ contributions Acknowledgements Introduction Retinoic TPEN is a key signalling molecule in healthy development and in differentiation of stem cells, albeit uncontrolled levels of retinoic acid can lead to mutagenesis [1]. In eukaryotes retinoic acid is made by oxidation of all-tran
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We used two different VSMCs cell lines KSB and
2020-08-14
We used two different VSMCs cell lines, KSB and CSD (isolated from two different thoracic aortas). Rat aortic VSMCs were isolated from medial segments from thoracic rate BIO-acetoxime receptor from Wistar-Kyoto rats (six to eight weeks old, Charles River Wiga GmbH) and cultured over several passages
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SMER 3 br Concluding Remarks Synthetic cytokine biology has
2020-08-14
Concluding Remarks Synthetic cytokine biology has become an important research area with novel solutions and ideas for therapeutic approaches, for example, synthekines, fusokines, immunocytokines, neoleukins, MESA receptors, or synthetic Notch or cytokine receptors. In addition to their huge impa
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Introduction br CK in the Regulation of Hh
2020-08-14
Introduction CK1 in the Regulation of Hh Pathway CK1 was initially identified as a negative regulator of Hh signaling at the level of transcription factor Ci by genetic studies in Drosophila and genome-wide RNAi screen in Drosophila cultured iMDK australia (Jia et al., 2005, Lum et al., 2003, P
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The interaction of EPAC with Rim has
2020-08-13
The interaction of EPAC2 with Rim1 has an important role in regulating neurotransmitter release. In addition, a recent EPAC2 knockout mice model study provides evidence that EPAC2 promotes transmitter release by maintaining the readily releasable pool (RRP) at mossy fiber (MF) synapses in the hippoc
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