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To extend these toxicity minimization strategies to D tissue
2020-10-30
To extend these toxicity minimization strategies to 3D tissues, a more complicated mass transfer model is necessary to account diffusion in the interstitial space, as well as transport across cell membranes. Until recently, tissue mass transport in cryobiology was modeled using classic spatially dep
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For any vector let and For let The information
2020-10-30
For any vector , let , and . For , let The information matrix for the partial likelihood at Eq. (2.2) can be expressed as It is well known that methylphenidate hcl receptor under certain regularity conditions such as (A)–(D) in Andersen and Gill (1982), where and denote the maximum likelihood
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Recent studies showed that the activity of CK was
2020-10-30
Recent studies showed that the activity of CK2 was significantly reduced in ischemic stroke model rats, and cerebral I/R injury significantly decreased the expression of CK2α (Lee et al., 2004; Kim et al., 2012; Zhou et al., 2016). In addition, the dysregulation of CK2 is involved in ERS/UPR in non
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To our knowledge this is the first report of an
2020-10-30
To our knowledge, this is the first report of an oncocytoma expressing alpha-enolase or causing autoimmune retinopathy and optic neuropathy. Although generally considered benign, oncocytomas have rarely been associated with paraneoplastic syndromes, including tumor-induced hypertension, erythrocytos
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br Acknowledgments We thank our colleagues who
2020-10-29
Acknowledgments We thank our colleagues who have contributed to our understanding of the CGP 3466B maleate and the structure and function of APC/C, and apologize to those whose work we were unable to cite here. We thank J. Rajan Prabu for making the movies showing APC/C conformational changes. Ou
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br Introduction br Structure of the Ku
2020-10-29
Introduction Structure of the Ku heterodimer associated to DNA The atomic structure of the Ku heterodimer, alone and bound to a small DNA fragment, was recently determined (Walker et al., 2001) and has significantly improved our understanding of DNA recognition by DNA-PK holoenzyme (Fig. 3). B
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tetraethylammonium Substituents at the C position An oxygen
2020-10-29
Substituents at the C11 position — An oxygen-containing substituent at the C11 position also affects the catalytic activity of Δ1-KSTDs. The Δ1-KSTDs from the Gram-positive bacteria R. equi [29], N. simplex ATCC 6946 and IFO 12069 [48,49,52], and R. rhodochrous IFO 3338 [27] were able to 1(2)-dehydr
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To better understand Wolbachia s
2020-10-29
To better understand Wolbachia’s dependence on these enzymes, RNAi experiments targeting these transcripts will be required to examine the consequences of their down-regulation on Wolbachia in the different tissues of the parasite. Initial studies have shown that decreases in Bm-cpl-3 and Bm-cpl-6 t
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br Role of cysLT signaling on
2020-10-29
Role of cysLT signaling on various neurological complications which are associated with Alzheimer’s disease Alzheimer’s disease, first described in 1906 by Alois Alzheimer, is a neurodegenerative disease and a very common cause of dementia progressively leading to death. Even though years of rese
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Opiate withdrawal promotes the activation of
2020-10-29
Opiate withdrawal promotes the activation of the corticotropin-releasing factor (CRF) system, a major coordinator of neuroendocrine and behavioral responses to stressors. For instance, early (8–48 h) morphine withdrawal is associated with increased CRF mRNA expression in the central nucleus of the a
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CRF and urocortin I are not only readily
2020-10-29
CRF and urocortin I are not only readily found throughout the spinal cord (Korosi et al., 2007), CRF analogs are clearly able to alter nociceptive signals (Imbe et al., 2010; Lariviere and Melzack, 2000). However, it was unclear whether they are released endogenously and involved in the spinal modul
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Pahlavanzadeh and Fakouri Baygi employed
2020-10-29
Pahlavanzadeh and Fakouri-Baygi [6] employed PC-SAFT EoS to predict the Anastrozole australia of carbon dioxide by aqueous MEA solutions. They used the ideal form of Smith–Missen algorithm to calculate liquid phase concentrations. The results illustrate acceptable accuracies so that the AAD was ach
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Interestingly Carver Johnson and Kim investigated a polymorp
2020-10-29
Interestingly, Carver, Johnson, and Kim (2016) investigated a polymorphism in the OPRM1 μ-opioid receptor gene for its role in sensitivity to social contexts. The G allele of this polymorphism was associated with higher levels of sensitivity. The authors found significant interactions, e.g. the nega
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br Methods br Results Main characteristics of study
2020-10-29
Methods Results Main characteristics of study population are presented in Table 1. AD cases had higher co-morbidity score and lower socioeconomic position than controls. Women with AD had undergone any surgery (unilateral/bilateral oophorectomy, hysterectomy, hysterectomy with bilateral oophor
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However with regard to the involvement of PEP in
2020-10-29
However, with regard to the involvement of PEP in neoplastic processes, few studies and restricted to a very limited number of different tumors have been carried out [4], [18], [19]. Therefore, in order to ascertain the possible role of this enzyme in pathological proliferative tissues, in the prese
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